Pharmacogenetic testing
نویسندگان
چکیده
منابع مشابه
Pharmacogenetic Testing-An Unfulfilled Promise.
The Human Genome Project heralded great hope that the clinical use of individual genetic information would result in improved care through treatments tailored to an individual patient’s genotype. Such treatment would presumably reveal individual susceptibility to chronic diseases, thus preventing them, and lead to targeted pharmacotherapies based on an individual’s metabolism and susceptibility...
متن کاملIs pharmacogenetic CYP2D6 testing useful?
BACKGROUND Pharmacogenetic testing is used to uncover genetic causes for variations in drug response. Documentation of the method's usefulness in a clinical setting is scarce. The aim of the study was to systematically categorize the experience from routine CYP2D6 genotyping in a diagnostic laboratory. MATERIAL AND METHODS All samples submitted to our laboratory for CYP2D6 genotyping in the p...
متن کاملPatients' and physicians' perspectives on pharmacogenetic testing.
INTRODUCTION The integration of pharmacogenetic testing into routine care will, in part, depend upon the patients' and physicians' acceptance of these tests. Empirical data regarding patients' and physicians' views on pharmacogenetic testing are lacking. OBJECTIVES To explore patients' and physicians' perspectives on the potential implications of pharmacogenetic testing, particularly focusing...
متن کاملPharmacogenetic testing: time for clinical practice guidelines.
Our knowledge regarding genetic factors that affect drug effectiveness and adverse drug reactions is continuously increasing, and a growing number of pharmacogenetic gene– drug interactions are included in drug labels. Nevertheless, the uptake of this important information into clinical practice has been minimal. The development of concise, evidence-based clinical practice guidelines (CPGs) on ...
متن کاملPharmacogenetic testing in population of South Ural.
BACKGROUND Drug resistance is a phenomenon that has received serious attention in recent years in everyday medical practice. This may also be described as responsiveness or non-responsiveness to drugs, as patients respond partially to medical treatment or have no response at all [1]. The non-responsiveness to clopidogrel in cardiac patients of different populations is due to genetic variations ...
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ژورنال
عنوان ژورنال: The Nurse Practitioner
سال: 2021
ISSN: 0361-1817
DOI: 10.1097/01.npr.0000737180.73290.1f